Abstract The coronavirus disease 19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global health crisis with millions of confirmed cases and related deaths.The main protease (Mpro) of SARS-CoV-2 is crucial for viral replication and presents an attractive target for drug development.Despite the approva
The successful establishment of a species in a given habitat depends on the ability of each of its developing stages to adapt to the environment.In order to understand this process we have studied the adaptation welding mirror with magnet of a euryhaline fish, the sea-bass Dicentrarchus labrax, to various salinities during its ontogeny.The expressi
IntroductionWe studied the distribution and in vitro pathogenicity of anti-DSG3 IgG subclasses during the course of pemphigus vulgaris (PV).MethodsWe longitudinally studied the distribution of anti-DSG3 IgG subclasses (before versus after treatment) in sera from PV patients, using an addressable-laser bead immunoassay (ALBIA).The in vitro pathogeni
Autism spectrum disorder (ASD) is increasingly common with 1 in 59 children in the United States currently meeting the diagnostic criteria.Altered sensory processing is typical in ASD, with auditory sensitivities being especially common; in volleyball replacement net particular, people with ASD frequently show heightened sensitivity to environmenta